Irradiation of regional nodes in stage I - III breast cancer patients affects overall survival

(European Organisation for Research and Treatment of Cancer) At a median follow-up of 10.9 years, an EORTC study has shown that irradiation of regional nodes in patients with stage I, II, or III breast cancer has a marginal effect on overall survival, the primary endpoint (at 10 years, overall survival was 82.3 percent for regional irradiation versus 80.7 percent for no regional irradiation).